Ralf Gerhard Selected Research

Pseudomembranous Enterocolitis (Pseudomembranous Colitis)

1/2021	The Binary Toxin of Clostridioides difficile Alters the Proteome and Phosphoproteome of HEp-2 Cells.
1/2021	Clostridioides difficile Toxin CDT Induces Cytotoxic Responses in Human Mucosal-Associated Invariant T (MAIT) Cells.
6/2015	Human neutrophils are activated by a peptide fragment of Clostridium difficile toxin B presumably via formyl peptide receptor.
2/2015	Clostridium difficile toxin B inhibits the secretory response of human mast cell line-1 (HMC-1) cells stimulated with high free-Ca²⁺ and GTPγS.
3/2011	Down-regulation of interleukin-16 in human mast cells HMC-1 by Clostridium difficile toxins A and B.
3/2011	Autoproteolytic cleavage mediates cytotoxicity of Clostridium difficile toxin A.
8/2007	Clostridium difficile toxins A and B directly stimulate human mast cells.
4/2006	Cholesterol-dependent pore formation of Clostridium difficile toxin A.
1/2003	The complete receptor-binding domain of Clostridium difficile toxin A is required for endocytosis.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Ralf Gerhard Research Topics

Disease

9	Pseudomembranous Enterocolitis (Pseudomembranous Colitis) 01/2021 - 01/2003
4	Infections 01/2021 - 01/2017
3	Diarrhea 01/2021 - 04/2006
2	Leukemia 03/2009 - 02/2007
1	Inflammation (Inflammations) 04/2022
1	Necrosis 04/2022
1	Cross Infection (Nosocomial Infection) 01/2021
1	Clostridium Infections 01/2021
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 11/2020
1	Carcinoma (Carcinomatosis) 01/2020
1	Blister (Bulla) 11/2014
1	Cholestasis 01/2012
1	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 01/2012
1	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 12/2011
1	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2011
1	Coinfection 03/2010

Drug/Important Bio-Agent (IBA)

8	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 01/2003
7	trimethylaminocarboxyldihydroboran (TCDB)IBA 04/2022 - 08/2007
6	Virulence Factors (Pathogenicity Factors)IBA 01/2021 - 01/2003
3	rho GTP-Binding Proteins (rho GTP-Binding Protein)IBA 04/2022 - 01/2003
3	ExotoxinsIBA 01/2021 - 01/2018
2	Proteins (Proteins, Gene)FDA Link 12/2011 - 03/2010
2	Cytotoxins (Cytolysins)IBA 04/2006 - 01/2003
1	Apolipoprotein C-IIIIBA 04/2022
1	chondroitin sulfate proteoglycan 4IBA 01/2021
1	chlorambucil-docosahexaenoic acid conjugateIBA 01/2021
1	Semaphorins (Semaphorin)IBA 01/2020
1	GlucosyltransferasesIBA 11/2014
1	ChromatinIBA 11/2014
1	ursodoxicoltaurineIBA 01/2012
1	Pharmaceutical PreparationsIBA 01/2012
1	Bile Acids and Salts (Bile Acids)IBA 01/2012
1	Profilins (Profilin)IBA 12/2011
1	rho-Associated KinasesIBA 12/2011
1	Phosphotransferases (Kinase)IBA 03/2009
1	ThymidineIBA 02/2007
1	Clostridium difficile tcdA proteinIBA 01/2003

Therapy/Procedure

1	Therapeutics 01/2017